NuvOx Pharma’s NVX-208 Shows Positive Results in Phase Ib/II Stroke Trial

Positive results of NuvOx Pharma’s NVX-208 in the treatment of stroke have been published at the International Stroke Conference.  The trial was sponsored by the University of Arkansas for Medical Sciences. William “Bill” Culp, MD, the principal investigator on the trial, said, “Such strong safety and promising efficacy results meet our highest hopes for this small trial. Expanded trials are fully warranted.”

The randomized Phase Ib/II trial tested acute ischemic stroke patients given placebo or low, medium, or high doses of NVX-208. The primary endpoint was safety, which was demonstrated at all three dose levels. A secondary endpoint was the modified Rankin Scale (mRS), a measure of how independently patients can live in the weeks and months after the stroke. The high dose group suggested improvement in the mRS at 30 days and 90 days.

The trial was sponsored by the University of Arkansas for Medical Sciences. William “Bill” Culp, MD, the principal investigator on the trial, said, “Such strong safety and promising efficacy results meet our highest hopes for this small trial. Expanded trials are fully warranted.”

NuvOx Pharma’s NVX-208 Shows Positive Results in Phase Ib/II Stroke Trial