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ZelosDx
Series A
Convertible Note
02/2014

ZelosDx

Originally founded as MsDx, ZelosDx provides novel biomarker tools for studying disease processes. The company is focused on commercializing both Research Use Only and In Vitro Diagnostic blood test products that will be used in monitoring neurological, autoimmune, and inflammatory disorders.

Accelerating Breakthrough Discoveries in Brain Disease

It is the mission of ZelosDx to provide researchers with novel blood testing tools that accelerate breakthrough discoveries.

ZelosDx’s Solution

A discovery made by ZelosDx presents a unique opportunity to combine the need for easy access to brain biomarkers with a sufficiently high level for their detection. It was found that the phagocytic cells that were recruited to the brain to clear the debris of neurodegeneration can then re-enter the blood circulation where they can be easily obtained through a blood sample. Peripheral blood monocytes provide a novel enriched source of brain-derived biomarkers. Since phagocytes in the blood are short-lived, their content of brain-specific debris is an indicator of recent damage and may be used as a marker of active neurodegeneration. Hence it may be viewed as a type of brain biopsy providing information about pathological changes in the brain.